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Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness

Carbonic anhydrase IX has been under intensive investigation as a therapeutic target in cancer. Studies demonstrate that this enzyme has a key role in pH regulation in cancer cells, allowing these cells to adapt to the adverse conditions of the tumour microenviroment. Novel CAIX inhibitors have show...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Metabolites
Hauptverfasser: Ward, Carol, Meehan, James, Gray, Mark, Kunkler, Ian H., Langdon, Simon P., Argyle, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874614/
https://ncbi.nlm.nih.gov/pubmed/29439394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo8010013
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