Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models

Triple negative, resistant or metastatic disease are major factors in breast cancer mortality, warranting novel approaches. Carbonic anhydrase IX (CAIX) is implicated in survival, migration and invasion of breast cancer cells and inhibition provides an innovative therapeutic strategy. The efficacy o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ward, Carol, Meehan, James, Mullen, Peter, Supuran, Claudiu, Dixon, J. Michael, Thomas, Jeremy S., Winum, Jean-Yves, Lambin, Philippe, Dubois, Ludwig, Pavathaneni, Nanda-Kumar, Jarman, Edward J., Renshaw, Lorna, Um, InHwa, Kay, Charlene, Harrison, David J., Kunkler, Ian H., Langdon, Simon P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694798/
https://ncbi.nlm.nih.gov/pubmed/26259239
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