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Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness

Carbonic anhydrase IX has been under intensive investigation as a therapeutic target in cancer. Studies demonstrate that this enzyme has a key role in pH regulation in cancer cells, allowing these cells to adapt to the adverse conditions of the tumour microenviroment. Novel CAIX inhibitors have show...

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Опубликовано в: :Metabolites
Главные авторы: Ward, Carol, Meehan, James, Gray, Mark, Kunkler, Ian H., Langdon, Simon P., Argyle, David J.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874614/
https://ncbi.nlm.nih.gov/pubmed/29439394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo8010013
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