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Monoclonal Antibodies against Occludin Completely Prevented Hepatitis C Virus Infection in a Mouse Model

Hepatitis C virus (HCV) entry into host cells is a multistep process requiring various host factors, including the tight junction protein occludin (OCLN), which has been shown to be essential for HCV infection in in vitro cell culture systems. However, it remains unclear whether OCLN is an effective...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Shimizu, Yoshimi, Shirasago, Yoshitaka, Kondoh, Masuo, Suzuki, Tetsuro, Wakita, Takaji, Hanada, Kentaro, Yagi, Kiyohito, Fukasawa, Masayoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874423/
https://ncbi.nlm.nih.gov/pubmed/29437969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02258-17
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