Monoclonal Antibodies against Occludin Completely Prevented Hepatitis C Virus Infection in a Mouse Model

Hepatitis C virus (HCV) entry into host cells is a multistep process requiring various host factors, including the tight junction protein occludin (OCLN), which has been shown to be essential for HCV infection in in vitro cell culture systems. However, it remains unclear whether OCLN is an effective...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Shimizu, Yoshimi, Shirasago, Yoshitaka, Kondoh, Masuo, Suzuki, Tetsuro, Wakita, Takaji, Hanada, Kentaro, Yagi, Kiyohito, Fukasawa, Masayoshi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2018
Aiheet:
Vaccines and Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874423/
https://ncbi.nlm.nih.gov/pubmed/29437969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02258-17
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