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The exclusive effects of chaperonin on the behavior of proteins with 5(2) knot

The folding of proteins with a complex knot is still an unresolved question. Based on representative members of Ubiquitin C-terminal Hydrolases (UCHs) that contain the 5(2) knot in the native state, we explain how UCHs are able to unfold and refold in vitro reversibly within the structure-based mode...

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Publicat a:PLoS Comput Biol
Autors principals: Zhao, Yani, Dabrowski-Tumanski, Pawel, Niewieczerzal, Szymon, Sulkowska, Joanna I.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874080/
https://ncbi.nlm.nih.gov/pubmed/29547629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005970
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