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The exclusive effects of chaperonin on the behavior of proteins with 5(2) knot
The folding of proteins with a complex knot is still an unresolved question. Based on representative members of Ubiquitin C-terminal Hydrolases (UCHs) that contain the 5(2) knot in the native state, we explain how UCHs are able to unfold and refold in vitro reversibly within the structure-based mode...
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| Publié dans: | PLoS Comput Biol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5874080/ https://ncbi.nlm.nih.gov/pubmed/29547629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005970 |
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