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Knotting and unknotting proteins in the chaperonin cage: Effects of the excluded volume

Molecular dynamics simulations are used to explore the effects of chaperonin-like cages on knotted proteins with very low sequence similarity, different depths of a knot but with a similar fold, and the same type of topology. The investigated proteins are VirC2, DndE and MJ0366 with two depths of a...

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Foilsithe in:PLoS One
Main Authors: Niewieczerzal, Szymon, Sulkowska, Joanna I.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425179/
https://ncbi.nlm.nih.gov/pubmed/28489858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176744
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