The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network

Epithelial tumor cells undergo epithelial-to-mesenchymal transition (EMT) to gain metastatic activity. Competing endogenous RNAs (ceRNAs) have binding sites for a common set of microRNAs (miRs) and regulate each other’s expression by sponging miRs. Here, we address whether ceRNAs govern metastasis d...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Tan, Xiaochao, Banerjee, Priyam, Liu, Xin, Yu, Jiang, Gibbons, Don L., Wu, Ping, Scott, Kenneth L., Diao, Lixia, Zheng, Xiaofeng, Wang, Jing, Jalali, Ali, Suraokar, Milind, Fujimoto, Junya, Behrens, Carmen, Liu, Xiuping, Liu, Chang-gong, Creighton, Chad J., Wistuba, Ignacio I., Kurie, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873879/
https://ncbi.nlm.nih.gov/pubmed/29324442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97225
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