Caricamento...
Translational repression of HIF2α expression in mice with Chuvash polycythemia reverses polycythemia
Chuvash polycythemia is an inherited disease caused by a homozygous germline VHL(R200W) mutation, which leads to impaired degradation of HIF2α, elevated levels of serum erythropoietin, and erythrocytosis/polycythemia. This phenotype is recapitulated by a mouse model bearing a homozygous Vhl(R200W) m...
Salvato in:
| Pubblicato in: | J Clin Invest |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2018
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5873849/ https://ncbi.nlm.nih.gov/pubmed/29480820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97684 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|