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Multi-functional effects of a small-molecule STAT3 inhibitor on NASH and HCC in mice

PURPOSE: The incidence of hepatocellular carcinoma (HCC) is increasing in the United States and liver cancer is the second leading cause of cancer-related mortality worldwide. Non-alcoholic steatohepatitis (NASH) is becoming an important risk for HCC and most patients with HCC have underlying liver...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Jung, Kwang Hwa, Yoo, Wonbeak, Stevenson, Heather L., Deshpande, Dipti, Shen, Hong, Gagea, Mihai, Yoo, Suk-Young, Wang, Jing, Eckols, T. Kris, Bharadwaj, Uddalak, Tweardy, David J., Beretta, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873583/
https://ncbi.nlm.nih.gov/pubmed/28533225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2253
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