Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance

Doxorubicin (DOX), an anthracycline, is broadly considered the most active single agent available for treating breast cancer but has been known to induce cardiotoxicity. Although DOX is highly effective in treating triple-negative breast cancer (TNBC), DOX can have poor outcomes owing to induction o...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Robinson, Prema, Kasembeli, Moses, Bharadwaj, Uddalak, Engineer, Nikita, Eckols, Kris T., Tweardy, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766315/
https://ncbi.nlm.nih.gov/pubmed/26981525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1959270
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