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Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance

Doxorubicin (DOX), an anthracycline, is broadly considered the most active single agent available for treating breast cancer but has been known to induce cardiotoxicity. Although DOX is highly effective in treating triple-negative breast cancer (TNBC), DOX can have poor outcomes owing to induction o...

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Publicat a:Biomed Res Int
Autors principals: Robinson, Prema, Kasembeli, Moses, Bharadwaj, Uddalak, Engineer, Nikita, Eckols, Kris T., Tweardy, David J.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766315/
https://ncbi.nlm.nih.gov/pubmed/26981525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1959270
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