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Ligand Binding Site Structure Influences the Evolution of Protein Complex Function and Topology

It has been suggested that the evolution of protein complexes is significantly influenced by stochastic, non-adaptive processes. Using ligand binding as a proxy of function, we show that the structure of ligand-binding sites significantly influences the evolution of protein complexes. We show that h...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Abrusán, György, Marsh, Joseph A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873459/
https://ncbi.nlm.nih.gov/pubmed/29562182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.085
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