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Binding site identification and structure determination of protein-ligand complexes by NMR
Over the last fifteen years, the role of NMR spectroscopy in the lead identification and optimization stages of pharmaceutical drug discovery has steadily increased. NMR occupies a unique niche in the biophysical analysis of drug-like compounds because of its ability to identify binding sites, affin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635485/ https://ncbi.nlm.nih.gov/pubmed/21371594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381274-2.00010-8 |
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