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Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite

The dorsal–ventral polarity of the somite is controlled by antagonistic signals from the dorsal neural tube/surface ectoderm, mediated by WNTs, and from the ventral notochord, mediated by sonic hedgehog (SHH). Each factor can act over a distance greater than a somite diameter in vitro, suggesting th...

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Autores principales: Lee, Catherine S., Buttitta, Laura, Fan, Chen-Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC58732/
https://ncbi.nlm.nih.gov/pubmed/11572986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.201418298
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