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Peptide nucleic acid-templated selenocystine–selenoester ligation enables rapid miRNA detection

The development of a rapid and chemoselective selenocystine–selenoester peptide ligation that operates at nanomolar reactant concentrations has been developed by utilising PNA templation. Kinetic analysis of the templated peptide ligation revealed that the selenocystine–selenoester reaction was 10 t...

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Pubblicato in:Chem Sci
Autori principali: Sayers, Jessica, Payne, Richard J., Winssinger, Nicolas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873163/
https://ncbi.nlm.nih.gov/pubmed/29629156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc02736b
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