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Peptide nucleic acid-templated selenocystine–selenoester ligation enables rapid miRNA detection

The development of a rapid and chemoselective selenocystine–selenoester peptide ligation that operates at nanomolar reactant concentrations has been developed by utilising PNA templation. Kinetic analysis of the templated peptide ligation revealed that the selenocystine–selenoester reaction was 10 t...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Sayers, Jessica, Payne, Richard J., Winssinger, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873163/
https://ncbi.nlm.nih.gov/pubmed/29629156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc02736b
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