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Dynamics of P-type ATPase transport cycle revealed by single-molecule FRET
P-type ATPases are ubiquitous primary transporters that pump cations across cell membranes through the formation and breakdown of a phosphoenzyme intermediate. Structural investigations suggest a transport mechanism defined by conformational changes in the cytoplasmic domains of the protein that are...
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| Veröffentlicht in: | Nature |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5872817/ https://ncbi.nlm.nih.gov/pubmed/29144454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24296 |
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