Dynamics of P-type ATPase transport cycle revealed by single-molecule FRET

P-type ATPases are ubiquitous primary transporters that pump cations across cell membranes through the formation and breakdown of a phosphoenzyme intermediate. Structural investigations suggest a transport mechanism defined by conformational changes in the cytoplasmic domains of the protein that are...

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Bibliografske podrobnosti
izdano v:Nature
Main Authors: Dyla, Mateusz, Terry, Daniel S., Kjaergaard, Magnus, Sørensen, Thomas L-M, Andersen, Jacob Lauwring, Andersen, Jens Peter, Knudsen, Charlotte Rohde, Altman, Roger B., Nissen, Poul, Blanchard, Scott C.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872817/
https://ncbi.nlm.nih.gov/pubmed/29144454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24296
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