The Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 Inhibits Lipopolysaccharide-Induced Osteoclast Formation and Bone Resorption via Inhibition of TNF-α Expression in Macrophages

Glucagon-like peptide-1 (GLP-1) receptor agonists are an effective treatment approach for type 2 diabetes. Recently, anti-inflammatory effects of GLP-1 receptor agonists have also been reported. Lipopolysaccharide (LPS) induces inflammation and osteoclast formation. In this study, we investigated th...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Shen, Wei-Ren, Kimura, Keisuke, Ishida, Masahiko, Sugisawa, Haruki, Kishikawa, Akiko, Shima, Kazuhiro, Ogawa, Saika, Qi, Jiawei, Kitaura, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872659/
https://ncbi.nlm.nih.gov/pubmed/29725604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/5783639
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