Docosahexaenoic Acid Inhibits Inflammation-Induced Osteoclast Formation and Bone Resorption in vivo Through GPR120 by Inhibiting TNF-α Production in Macrophages and Directly Inhibiting Osteoclast Formation

Docosahexaenoic acid (DHA) is an n-3 fatty acid that is an important structural component of the cell membrane. DHA exerts potent anti-inflammatory effects through G protein-coupled receptor 120 (GPR120), which is a functional receptor for n-3 fatty acids. DHA also regulates osteoclast formation and...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Kishikawa, Akiko, Kitaura, Hideki, Kimura, Keisuke, Ogawa, Saika, Qi, Jiawei, Shen, Wei-Ren, Ohori, Fumitoshi, Noguchi, Takahiro, Marahleh, Aseel, Nara, Yasuhiko, Ichimura, Atsuhiko, Mizoguchi, Itaru
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436080/
https://ncbi.nlm.nih.gov/pubmed/30949128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00157
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