TNF-α Directly Enhances Osteocyte RANKL Expression and Promotes Osteoclast Formation

Osteoimmunology peeks into the interaction of bone and the immune system, which has largely proved to be a multiplex reaction. Osteocytes have been shown to regulate bone resorption through the expression of RANKL in physiologic and pathologic conditions. TNF-α, a product of the immune system, is an...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Marahleh, Aseel, Kitaura, Hideki, Ohori, Fumitoshi, Kishikawa, Akiko, Ogawa, Saika, Shen, Wei-Ren, Qi, Jiawei, Noguchi, Takahiro, Nara, Yasuhiko, Mizoguchi, Itaru
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923682/
https://ncbi.nlm.nih.gov/pubmed/31921183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02925
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