Muramyl Dipeptide Enhances Lipopolysaccharide-Induced Osteoclast Formation and Bone Resorption through Increased RANKL Expression in Stromal Cells

Lipopolysaccharide (LPS) is bacterial cell wall component capable of inducing osteoclast formation and pathological bone resorption. Muramyl dipeptide (MDP), the minimal essential structural unit responsible for the immunological activity of peptidoglycans, is ubiquitously expressed by bacterium. In...

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Detalles Bibliográficos
Publicado en:J Immunol Res
Main Authors: Ishida, Masahiko, Kitaura, Hideki, Kimura, Keisuke, Sugisawa, Haruki, Aonuma, Tomo, Takada, Haruhiko, Takano-Yamamoto, Teruko
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427123/
https://ncbi.nlm.nih.gov/pubmed/26000311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/132765
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