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Three-dimensional experiments and individual based simulations show that cell proliferation drives melanoma nest formation in human skin tissue

BACKGROUND: Melanoma can be diagnosed by identifying nests of cells on the skin surface. Understanding the processes that drive nest formation is important as these processes could be potential targets for new cancer drugs. Cell proliferation and cell migration are two potential mechanisms that coul...

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Detaylı Bibliyografya
Yayımlandı:BMC Syst Biol
Asıl Yazarlar: Haridas, Parvathi, Browning, Alexander P., McGovern, Jacqui A., Sean McElwain, D. L., Simpson, Matthew J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872522/
https://ncbi.nlm.nih.gov/pubmed/29587750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0559-9
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