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Three-dimensional experiments and individual based simulations show that cell proliferation drives melanoma nest formation in human skin tissue

BACKGROUND: Melanoma can be diagnosed by identifying nests of cells on the skin surface. Understanding the processes that drive nest formation is important as these processes could be potential targets for new cancer drugs. Cell proliferation and cell migration are two potential mechanisms that coul...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Haridas, Parvathi, Browning, Alexander P., McGovern, Jacqui A., Sean McElwain, D. L., Simpson, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872522/
https://ncbi.nlm.nih.gov/pubmed/29587750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0559-9
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