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Three-dimensional experiments and individual based simulations show that cell proliferation drives melanoma nest formation in human skin tissue
BACKGROUND: Melanoma can be diagnosed by identifying nests of cells on the skin surface. Understanding the processes that drive nest formation is important as these processes could be potential targets for new cancer drugs. Cell proliferation and cell migration are two potential mechanisms that coul...
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| Published in: | BMC Syst Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5872522/ https://ncbi.nlm.nih.gov/pubmed/29587750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0559-9 |
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