Caricamento...

SUMOylation Regulates Transcription by the Progesterone Receptor A Isoform in a Target Gene Selective Manner

Luminal breast cancers express estrogen (ER) and progesterone (PR) receptors, and respond to endocrine therapies. However, some ER+PR+ tumors display intrinsic or acquired resistance, possibly related to PR. Two PR isoforms, PR-A and PR-B, regulate distinct gene subsets that may differentially influ...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Diseases
Autori principali: Abdel-Hafiz, Hany A., Dudevoir, Michelle L., Perez, Daniel, Abdel-Hafiz, Mohamed, Horwitz, Kathryn B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871951/
https://ncbi.nlm.nih.gov/pubmed/29301281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diseases6010005
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !