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Mechanisms Underlying the Control of Progesterone Receptor Transcriptional Activity by SUMOylation

Posttranslational modification by small ubiquitin-like modifier (SUMO) is a major regulator of transcription. We previously showed that progesterone receptors (PR) have a single consensus ψKXE SUMO-conjugation motif centered at Lys-388 in the N-terminal domain of PR-B and a homologous site of PR-A....

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Detalhes bibliográficos
Main Authors: Abdel-Hafiz, Hany, Dudevoir, Michelle L., Horwitz, Kathryn B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666559/
https://ncbi.nlm.nih.gov/pubmed/19211567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805226200
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