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SUMOylation Regulates Transcription by the Progesterone Receptor A Isoform in a Target Gene Selective Manner
Luminal breast cancers express estrogen (ER) and progesterone (PR) receptors, and respond to endocrine therapies. However, some ER+PR+ tumors display intrinsic or acquired resistance, possibly related to PR. Two PR isoforms, PR-A and PR-B, regulate distinct gene subsets that may differentially influ...
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| Udgivet i: | Diseases |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5871951/ https://ncbi.nlm.nih.gov/pubmed/29301281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diseases6010005 |
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