Vitamin C preferentially kills cancer stem cells in hepatocellular carcinoma via SVCT-2

Vitamin C (L-ascorbic acid, ascorbate, VC) is a potential chemotherapeutic agent for cancer patients. However, the anti-tumor effects of pharmacologic VC on hepatocellular carcinoma (HCC) and liver cancer stem cells (CSCs) remain to be fully elucidated. Panels of human HCC cell lines as well as HCC...

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Bibliografiske detaljer
Udgivet i:NPJ Precis Oncol
Main Authors: Lv, Hongwei, Wang, Changzheng, Fang, Tian, Li, Ting, Lv, Guishuai, Han, Qin, Yang, Wen, Wang, Hongyang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871898/
https://ncbi.nlm.nih.gov/pubmed/29872720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-017-0044-8
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