Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion

A chronic viral or tumor microenvironment can push T cells to exhaustion by promoting coinhibitory ligand expression. However, how host factors control coinhibitory ligand expression and whether viral infection breaks this control during tumor progress is unknown. Here we show a close negative corre...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Sun, Cheng, Lan, Peixiang, Han, Qiuju, Huang, Mei, Zhang, Zhihong, Xu, Geliang, Song, Jiaxi, Wang, Jinyu, Wei, Haiming, Zhang, Jian, Sun, Rui, Zhang, Cai, Tian, Zhigang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871883/
https://ncbi.nlm.nih.gov/pubmed/29593314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03584-3
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items