Загрузка...

Vitamin C promotes apoptosis in breast cancer cells by increasing TRAIL expression

Genomic loss of 5-hydroxymethylcytosine (5hmC) accompanies malignant cellular transformation in breast cancer. Vitamin C serves as a cofactor for TET methylcytosine dioxygenases to increase 5hmC generation. Here we show that the transcription of SVCT2, a major vitamin C transporter, was decreased in...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Sant, David W., Mustafi, Sushmita, Gustafson, Christopher B., Chen, Joshua, Slingerland, Joyce M., Wang, Gaofeng
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871772/
https://ncbi.nlm.nih.gov/pubmed/29593282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23714-7
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!