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Vitamin C promotes apoptosis in breast cancer cells by increasing TRAIL expression
Genomic loss of 5-hydroxymethylcytosine (5hmC) accompanies malignant cellular transformation in breast cancer. Vitamin C serves as a cofactor for TET methylcytosine dioxygenases to increase 5hmC generation. Here we show that the transcription of SVCT2, a major vitamin C transporter, was decreased in...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5871772/ https://ncbi.nlm.nih.gov/pubmed/29593282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23714-7 |
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