Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC

Axon guidance involves the spatiotemporal interplay between guidance cues and membrane-bound cell-surface receptors, present on the growth cone of the axon. Netrin-1 is a prototypical guidance cue that binds to deleted in colorectal cancer (DCC), and it has been proposed that the guidance cue Draxin...

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Publicado no:Neuron
Main Authors: Liu, Ying, Bhowmick, Tuhin, Liu, Yiqiong, Gao, Xuefan, Mertens, Haydyn D.T., Svergun, Dmitri I., Xiao, Junyu, Zhang, Yan, Wang, Jia-huai, Meijers, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871715/
https://ncbi.nlm.nih.gov/pubmed/29503192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.02.010
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