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The crystal structure of netrin-1 in complex with DCC reveals the bi-functionality of netrin-1 as a guidance cue
Netrin-1 is a guidance cue that can trigger either attraction or repulsion effects on migrating neurons, depending on the repertoire of receptors available on the growth cone. How a single chemotropic molecule can act in such contradictory ways has long been a puzzle at the molecular level. Here we...
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| Publicat a: | Neuron |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4412161/ https://ncbi.nlm.nih.gov/pubmed/25123307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.07.010 |
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