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Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance

Netrin-1 acts as a chemoattractant molecule to guide commissural neurons (CN) toward the floor plate by interacting with the receptor deleted in colorectal cancer (DCC). The molecular mechanisms underlying Netrin-1–DCC signaling are still poorly characterized. Here, we show that DCC is phosphorylate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Meriane, Mayya, Tcherkezian, Joseph, Webber, Christine A., Danek, Eric I., Triki, Ibtissem, McFarlane, Sarah, Bloch-Gallego, Evelyne, Lamarche-Vane, Nathalie
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172574/
https://ncbi.nlm.nih.gov/pubmed/15557120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405053
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