Safety and tolerability of a novel, polyclonal human anti-MERS coronavirus antibody produced from transchromosomic cattle: a phase 1 randomised, double-blind, single-dose-escalation study

BACKGROUND: Middle East respiratory syndrome (MERS) is a severe respiratory illness with an overall mortality of 35%. There is no licensed or proven treatment. Passive immunotherapy approaches are being developed to prevent and treat several human medical conditions where alternative therapeutic opt...

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Publicado no:Lancet Infect Dis
Main Authors: Beigel, John H, Voell, Jocelyn, Kumar, Parag, Raviprakash, Kanakatte, Wu, Hua, Jiao, Jin-An, Sullivan, Eddie, Luke, Thomas, Davey, Richard T
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871563/
https://ncbi.nlm.nih.gov/pubmed/29329957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(18)30002-1
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