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Physiological Level Production of Antigen-Specific Human Immunoglobulin in Cloned Transchromosomic Cattle

Therapeutic human polyclonal antibodies (hpAbs) derived from pooled plasma from human donors are Food and Drug Administration approved biologics used in the treatment of a variety of human diseases. Powered by the natural diversity of immune response, hpAbs are effective in treating diseases caused...

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Autors principals: Sano, Akiko, Matsushita, Hiroaki, Wu, Hua, Jiao, Jin-An, Kasinathan, Poothappillai, Sullivan, Eddie J., Wang, Zhongde, Kuroiwa, Yoshimi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813428/
https://ncbi.nlm.nih.gov/pubmed/24205120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078119
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