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Differential effects of divalent cations on elk prion protein fibril formation and stability

Misfolding of the normally folded prion protein of mammals (PrP(C)) into infectious fibrils causes a variety of diseases, from scrapie in sheep to chronic wasting disease (CWD) in cervids. The misfolded form of PrP(C), termed PrP(Sc), or in this case PrP(CWD), interacts with PrP(C) to create more Pr...

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Bibliografske podrobnosti
izdano v:Prion
Main Authors: Samorodnitsky, Daniel, Nicholson, Eric M.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871030/
https://ncbi.nlm.nih.gov/pubmed/29310497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2017.1423187
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