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Epigenetic regulation of cell fate reprogramming in aging and disease: A predictive computational model
Understanding the control of epigenetic regulation is key to explain and modify the aging process. Because histone-modifying enzymes are sensitive to shifts in availability of cofactors (e.g. metabolites), cellular epigenetic states may be tied to changing conditions associated with cofactor variabi...
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| 出版年: | PLoS Comput Biol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5871006/ https://ncbi.nlm.nih.gov/pubmed/29543808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006052 |
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