Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

BACKGROUND: Despite repeated outbreaks, in particular the devastating 2014–2016 epidemic, there is no effective treatment validated for patients with Ebola virus disease (EVD). Among the drug candidates is the broad-spectrum polymerase inhibitor favipiravir, which showed a good tolerance profile in...

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Dades bibliogràfiques
Publicat a:PLoS Med
Autors principals: Guedj, Jérémie, Piorkowski, Géraldine, Jacquot, Frédéric, Madelain, Vincent, Nguyen, Thi Huyen Tram, Rodallec, Anne, Gunther, Stephan, Carbonnelle, Caroline, Mentré, France, Raoul, Hervé, de Lamballerie, Xavier
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870946/
https://ncbi.nlm.nih.gov/pubmed/29584730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002535
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