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An antigen-specific semi-therapeutic treatment with local delivery of tolerogenic factors through a dual-sized microparticle system blocks experimental autoimmune encephalomyelitis

Antigen-specific treatments are highly desirable for autoimmune diseases in contrast to treatments which induce systemic immunosuppression. A novel antigen-specific therapy has been developed which, when administered semi-therapeutically, is highly efficacious in the treatment of the mouse model for...

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Publicado no:Biomaterials
Main Authors: Cho, Jonathan J., Stewart, Joshua M., Drashansky, Theodore T., Brusko, Maigan A., Zuniga, Ashley N., Lorentsen, Kyle J., Keselowsky, Benjamin G., Avram, Dorina
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870833/
https://ncbi.nlm.nih.gov/pubmed/28772190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.07.029
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