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Tumor phylogeny inference using tree-constrained importance sampling

MOTIVATION: A tumor arises from an evolutionary process that can be modeled as a phylogenetic tree. However, reconstructing this tree is challenging as most cancer sequencing uses bulk tumor tissue containing heterogeneous mixtures of cells. RESULTS: We introduce Probabilistic Algorithm for Somatic...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bioinformatics
Egile Nagusiak: Satas, Gryte, Raphael, Benjamin J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870673/
https://ncbi.nlm.nih.gov/pubmed/28882002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx270
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