Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactions

BACKGROUND: Hippo/YAP pathway is known to be important for development, growth and organogenesis, and dysregulation of this pathway leads to tumor progression. We and others find that YAP is up-regulated in pancreatic ductal adenocarcinoma (PDAC) and associated with worse prognosis of patients. Acti...

Full description

Saved in:

Bibliographic Details
Published in:	J Exp Clin Cancer Res
Main Authors:	Jiang, Zhengdong, Zhou, Cancan, Cheng, Liang, Yan, Bin, Chen, Ke, Chen, Xin, Zong, Liang, Lei, Jianjun, Duan, Wanxing, Xu, Qinhong, Li, Xuqi, Wang, Zheng, Ma, Qingyong, Ma, Jiguang
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2018
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5870346/ https://ncbi.nlm.nih.gov/pubmed/29587800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0740-4
Tags:	Add Tag No Tags, Be the first to tag this record!

Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactions

Similar Items