Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactions

BACKGROUND: Hippo/YAP pathway is known to be important for development, growth and organogenesis, and dysregulation of this pathway leads to tumor progression. We and others find that YAP is up-regulated in pancreatic ductal adenocarcinoma (PDAC) and associated with worse prognosis of patients. Acti...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Jiang, Zhengdong, Zhou, Cancan, Cheng, Liang, Yan, Bin, Chen, Ke, Chen, Xin, Zong, Liang, Lei, Jianjun, Duan, Wanxing, Xu, Qinhong, Li, Xuqi, Wang, Zheng, Ma, Qingyong, Ma, Jiguang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870346/
https://ncbi.nlm.nih.gov/pubmed/29587800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0740-4
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