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Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactions
BACKGROUND: Hippo/YAP pathway is known to be important for development, growth and organogenesis, and dysregulation of this pathway leads to tumor progression. We and others find that YAP is up-regulated in pancreatic ductal adenocarcinoma (PDAC) and associated with worse prognosis of patients. Acti...
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| Published in: | J Exp Clin Cancer Res |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5870346/ https://ncbi.nlm.nih.gov/pubmed/29587800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0740-4 |
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