YAP Inhibition by Resveratrol via Activation of AMPK Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine

Resveratrol, a natural polyphenol present in most plants, inhibits the growth of numerous cancers both in vitro and in vivo. Aberrant expression of YAP has been reported to activate multiple growth-regulatory pathways and confer anti-apoptotic abilities to many cancer cells. However, the role of res...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhengdong Jiang, Xin Chen, Ke Chen, Liankang Sun, Luping Gao, Cancan Zhou, Meng Lei, Wanxing Duan, Zheng Wang, Qingyong Ma, Jiguang Ma
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2016-09-01
Colecção:Nutrients
Assuntos:
pancreatic cancer
resveratrol
AMPK
YAP
gemcitabine
Acesso em linha:http://www.mdpi.com/2072-6643/8/10/546
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados