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Genome-Wide Analyses Identify Filamin-A As a Novel Downstream Target for Insulin and IGF1 Action

Insulin analogs were developed to improve diabetes therapy. However, certain modifications introduced into the insulin molecule were shown to enhance their affinity to the insulin-like growth factor-1 receptor (IGF1R). Most tumors, including endometrial cancers, express high levels of IGF1R. The pre...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Endocrinol (Lausanne)
Main Authors: Aizen, Daniel, Pasmanik-Chor, Metsada, Sarfstein, Rive, Laron, Zvi, Bruchim, Ilan, Werner, Haim
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870203/
https://ncbi.nlm.nih.gov/pubmed/29615978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00105
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