Identification of thioredoxin-interacting protein (TXNIP) as a downstream target for IGF1 action

Laron syndrome (LS), or primary growth hormone (GH) insensitivity, is the best-characterized entity among the congenital insulin-like growth factor 1 (IGF1) deficiencies. Life-long exposure to minute endogenous IGF1 levels is linked to low stature as well as a number of endocrine and metabolic abnor...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nagaraj, Karthik, Lapkina-Gendler, Lena, Sarfstein, Rive, Gurwitz, David, Pasmanik-Chor, Metsada, Laron, Zvi, Yakar, Shoshana, Werner, Haim
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798358/
https://ncbi.nlm.nih.gov/pubmed/29339473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715930115
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