Genome-Wide Analyses Identify Filamin-A As a Novel Downstream Target for Insulin and IGF1 Action

Insulin analogs were developed to improve diabetes therapy. However, certain modifications introduced into the insulin molecule were shown to enhance their affinity to the insulin-like growth factor-1 receptor (IGF1R). Most tumors, including endometrial cancers, express high levels of IGF1R. The pre...

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Detalles Bibliográficos
Publicado en:Front Endocrinol (Lausanne)
Main Authors: Aizen, Daniel, Pasmanik-Chor, Metsada, Sarfstein, Rive, Laron, Zvi, Bruchim, Ilan, Werner, Haim
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Endocrinology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870203/
https://ncbi.nlm.nih.gov/pubmed/29615978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00105
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