Disruption of Claudin-1 Expression by miRNA-182 Alters the Susceptibility to Viral Infectivity in HCV Cell Models

HCV entry involves a complex interplay between viral and host molecules. During post-binding interactions, the viral E2 complexes with CD81 receptor for delivery to the tight junction proteins CLDN1 and OCLN, which aid in viral internalization. Targeting HCV entry receptors represents an appealing a...

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Udgivet i:Front Genet
Main Authors: Riad, Sarah E., Elhelw, Dalia S., Shawer, Heba, El-Ekiaby, Nada, Salah, Ayman, Zekri, Abdelrahman, Esmat, Gamal, Amleh, Asma, Abdelaziz, Ahmed I.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869927/
https://ncbi.nlm.nih.gov/pubmed/29616082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00093
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