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Disruption of Claudin-1 Expression by miRNA-182 Alters the Susceptibility to Viral Infectivity in HCV Cell Models

HCV entry involves a complex interplay between viral and host molecules. During post-binding interactions, the viral E2 complexes with CD81 receptor for delivery to the tight junction proteins CLDN1 and OCLN, which aid in viral internalization. Targeting HCV entry receptors represents an appealing a...

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Détails bibliographiques
Publié dans:Front Genet
Auteurs principaux: Riad, Sarah E., Elhelw, Dalia S., Shawer, Heba, El-Ekiaby, Nada, Salah, Ayman, Zekri, Abdelrahman, Esmat, Gamal, Amleh, Asma, Abdelaziz, Ahmed I.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869927/
https://ncbi.nlm.nih.gov/pubmed/29616082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00093
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